Bronchiolitis obliterans following hematopoietic stem cell transplantation

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Bronchiolitis obliterans following haematopoietic stem cell transplantation.

The aim of the present article is to review the available clinical data on bronchiolitis obliterans following haematopoietic stem cell transplantation (HSCT). The data sources used were the Medline database and references from the identified articles related to bronchiolitis obliterans, noninfectious pulmonary complications and HSCT. HSCT is an important treatment for a variety of malignant and...

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bronchiolitis obliterans following hematopoietic stem cell transplantation: risk factors and diagnostic methods

introduction: bronchiolitis obliterans (bo) is one of the most important pulmonary complications of hematopoietic stem cell transplantation (hsct). we decided to evaluate the prevalence and risk factors of bo in hsct patients in the shariati hospital oncology research center. materials and methods: forty two patients, who had had hsct for at least 6 months ago, completed the study. the diagnosi...

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Calcineurin inhibitors in bronchiolitis obliterans syndrome following stem cell transplantation.

Bronchiolitis obliterans is a complication after allogeneic haematopoietic stem cell transplantation (HSCT). Management of bronchiolitis obliterans comprises intensive immunosuppression, but treatment response is poor. We investigated the effect of cyclosporine A (CsA), tacrolimus (FK506), methylprednisolone (mPRED), mycophenolate mofetil (MMF) and everolimus on the proliferation of primary lun...

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Postinfectious bronchiolitis obliterans in children: lessons from bronchiolitis obliterans after lung transplantation and hematopoietic stem cell transplantation

Postinfectious bronchiolitis obliterans (PIBO) is an irreversible obstructive lung disease characterized by subepithelial inflammation and fibrotic narrowing of the bronchioles after lower respiratory tract infection during childhood, especially early childhood. Although diagnosis of PIBO should be confirmed by histopathology, it is generally based on history and clinical findings. Irreversible...

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Bronchiolitis obliterans following lung transplantation.

Bronchiolitis obliterans syndrome (BOS) is the main and late chronic complication after lung transplantation. It remains a major impediment to long-term outcome. Unfortunately, the survival rate of lung transplant recipients lags behind that of other organ transplant recipients, and BOS accounts for more than 30% of all mortality after the third year following lung transplantation. Most recent ...

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ژورنال

عنوان ژورنال: Hematology/Oncology and Stem Cell Therapy

سال: 2010

ISSN: 1658-3876

DOI: 10.1016/s1658-3876(10)50044-x